SOC Drugs

# 1. Target: GSR

Drugs

Model Evidence

7 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


2. Target: VEGFA

Drugs

Model Evidence

19 regulons containing the target(s), VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


Drugs in GBM Trials

# 1. Target: RRM2

Drugs

Model Evidence

12 regulons containing the target(s), RRM2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


2. Target: GPD2,NDUFA13

Drugs

Model Evidence

15 regulons containing the target(s), GPD2,NDUFA13 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


3. Target: FNTA,FNTB

Drugs

Model Evidence

13 regulons containing the target(s), FNTA,FNTB are overactive in this patient.

Hallmarks Enrichment

HALLMARK_OXIDATIVE_PHOSPHORYLATION

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


FDA Approved Drugs

# 1. Target: APP

Drugs

Model Evidence

41 regulons containing the target(s), APP are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


2. Target: GPD2,NDUFA13

Drugs

Model Evidence

15 regulons containing the target(s), GPD2,NDUFA13 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


3. Target: GSR

Drugs

Model Evidence

7 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


4. Target: UGCG

Drugs

Model Evidence

51 regulons containing the target(s), UGCG are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


5. Target: ABL1

Drugs

Model Evidence

5 regulons containing the target(s), ABL1 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


6. Target: NDUFA13

Drugs

Model Evidence

5 regulons containing the target(s), NDUFA13 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


7. Target: TSG101

Drugs

Model Evidence

2 regulons containing the target(s), TSG101 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


8. Target: NCAM1

Drugs

Model Evidence

1 regulons containing the target(s), NCAM1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


9. Target: ABAT

Drugs

Model Evidence

17 regulons containing the target(s), ABAT are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


10. Target: TRPV4

Drugs

Model Evidence

1 regulons containing the target(s), TRPV4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


11. Target: RRM2

Drugs

Model Evidence

12 regulons containing the target(s), RRM2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


12. Target: SERPINE1

Drugs

Model Evidence

51 regulons containing the target(s), SERPINE1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


13. Target: TNC

Drugs

Model Evidence

9 regulons containing the target(s), TNC are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


14. Target: MAPK1,MAPK3

Drugs

Model Evidence

18 regulons containing the target(s), MAPK1,MAPK3 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


15. Target: FNTA,FNTB

Drugs

Model Evidence

13 regulons containing the target(s), FNTA,FNTB are overactive in this patient.

Hallmarks Enrichment

HALLMARK_OXIDATIVE_PHOSPHORYLATION

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


16. Target: ATP1A1

Drugs

Model Evidence

64 regulons containing the target(s), ATP1A1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


17. Target: JAK2

Drugs

Model Evidence

17 regulons containing the target(s), JAK2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


18. Target: HSPA8

Drugs

Model Evidence

25 regulons containing the target(s), HSPA8 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


19. Target: SOD1

Drugs

Model Evidence

5 regulons containing the target(s), SOD1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


20. Target: ACVR2B

Drugs

Model Evidence

5 regulons containing the target(s), ACVR2B are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


21. Target: VEGFA

Drugs

Model Evidence

19 regulons containing the target(s), VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


22. Target: EEF2

Drugs

Model Evidence

9 regulons containing the target(s), EEF2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots

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